Fluid repletion and maintenance

Diminish duration and frequency of diarrhea with

1. Loperamide

Loperamide is often avoided when C. difficile is suspected.

Patients taking loperamide should be cautioned not to exceed the maximum daily dose.

2. Bismuth salicylates\

• Adult dose: 524 mg every 30 min to 1 hr as needed (regular strength) or 1050 mg every 60 min (maximum strength) for up to 2 days (maximum dose of approximately 4,200 mg)¹

3. Hospitalized patient who has a

a. persistent fever

b. bloody diarrhea,

severe abdominal pain,

symptoms of volume depletion (eg, dark or scant urine, symptoms of orthostasis),

or a history of inflammatory bowel disease,

complex medical history of immunosuppression (eg, because of treatment for malignancy, history of transplantation, or advanced human immunodeficiency virus [HIV] infection) or

significant vascular or cardiovascular disease.

Determine the Cause